Microbial Transformation of 3,3-Dimethylcyclohexyl methyl ketone and Antimicrobial Evaluation

نویسندگان

چکیده

3,3-Dimethylcyclohexyl methyl ketone (Herbac®) is a fine fragrance compound used in the cosmetic industry. In this study, biological derivatisation of substrate 3,3-dimethylcyclohexyl by 18 fungal cultures was carried out to obtain new derivatives. Among evaluated, plant fungus Aspergillus niger ATCC 10549, biotransformed 4-hydroxy derivative 19% yield. The structure determined using NMR and GC-MS spectroscopic methods. addition, antimicrobial activity Herbac® with metabolite against panel pathogenic microbial strains were evaluated vitro microdilution. results showed that relatively more susceptible compared Herbac®.

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ژورنال

عنوان ژورنال: Hacettepe Journal of Biology and Chemistry

سال: 2022

ISSN: ['1303-5002']

DOI: https://doi.org/10.15671/hjbc.982977